Detalhe da pesquisa
1.
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Cell;
184(8): 2167-2182.e22, 2021 04 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33811809
2.
Relation of insulin treatment for type 2 diabetes to the risk of major adverse cardiovascular events after acute coronary syndrome: an analysis of the BETonMACE randomized clinical trial.
Cardiovasc Diabetol;
20(1): 125, 2021 06 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34158057
3.
Apabetalone Mediated Epigenetic Modulation is Associated with Favorable Kidney Function and Alkaline Phosphatase Profile in Patients with Chronic Kidney Disease.
Kidney Blood Press Res;
43(2): 449-457, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29566379
4.
Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease.
Cardiovasc Ther;
2020: 9397109, 2020.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32821285
5.
Apabetalone downregulates factors and pathways associated with vascular calcification.
Atherosclerosis;
280: 75-84, 2019 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30476723
6.
Apabetalone lowers serum alkaline phosphatase and improves cardiovascular risk in patients with cardiovascular disease.
Atherosclerosis;
290: 59-65, 2019 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31568963
7.
Apabetalone (RVX-208) reduces vascular inflammation in vitro and in CVD patients by a BET-dependent epigenetic mechanism.
Clin Epigenetics;
11(1): 102, 2019 07 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31300040
8.
Benefit of Apabetalone on Plasma Proteins in Renal Disease.
Kidney Int Rep;
3(3): 711-721, 2018 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29854980
9.
Downregulation of the Complement Cascade In Vitro, in Mice and in Patients with Cardiovascular Disease by the BET Protein Inhibitor Apabetalone (RVX-208).
J Cardiovasc Transl Res;
10(4): 337-347, 2017 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28567671
10.
RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease.
Atherosclerosis;
247: 48-57, 2016 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26868508
11.
Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes.
Data Brief;
8: 1280-8, 2016 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27570805
12.
Corrigendum to "RVX-208, a BET-inhibitor for treating atherosclerotic cardiovascular disease, raises ApoA-I/HDL and represses pathways that contribute to cardiovascular disease" [Atherosclerosis 247 (2016) 48-57].
Atherosclerosis;
253: 345, 2016 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27211480
13.
Avian flu: the creation of expectations in the interplay between science and the media.
Sociol Health Illn;
29(1): 46-65, 2007 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17286705